Human IFN-gamma Precoated ELISA Kit
$599.00
Product will arrive in 1 to 2 business days
Key Features
✓ Assay Range: 15.6-1000 pg/mL
✓ Sensitivity: 5 pg/mL
✓ Sample Types: Serum, Plasma, Cell Culture Supernates
Size
✓ 1 Kit (96 well plate)
Need Help Ordering?
Product Details
Storage & Preparation
Data Images
Background
Product Documents
Product Details
| Product Type | Quantitative ELISA, Colorimetric |
| Product Summary |
|
| Reactivity | Human IFN-gamma
|
| Product Components |
|
Storage & Preparation
| Shipping | Shipped at ambient temperature |
| Stability & Storage | Store the unopened kit at 2-8℃, The kit is stable for 12 months. Do not use beyond expiration date. |
| Reconstitution | See Datasheet for Component Preparation |
Data Images
Human IFN-gamma ELISA standard curve, typical data. User-generated standard curve is required for each set of samples. Please refer to protocol.
Background
| Alternative Names | Interferon gamma, IFNG, Immune Interferon, IFG, IFI |
| Function | Interferon-gamma (IFN-gamma) is a protein with predominant roles in the innate and adaptive immune response. It is secreted by Th1 cells, cytotoxic T cells, macrophages, dendritic cells, mucosal epithelial cells and NK cells. IFN-gamma promotes the differentiation of T cells into Th1 cells. Th1 cells produce IFN-gamma themselves, creating a positive feedback loop that amplifies the immune response. In addition, IFN-gamma upregulates monocytes, macrophages, and dendritic cells while increasing MHC class I and II expression. B Cell immunoglobulin class switching is also influenced by IFN-gamma. IFN-gamma RI (CD119/IFNGR1) is the ligand-binding subunit that heterodimerizes with the IFN-gamma RII (IFNGR2). |
| Tissue Specificity | IFN-gamma expression has been identified in vascular endothelial cells, respiratory and gastrointestinal epithelial cells. |
| Cellular Localization | Secreted protein |
| Involvement in Disease | Dysregulation of IFN-gamma is associated with autoimmune disorders (multiple sclerosis (MS), rheumatoid arthritis (RA), type 1 diabetes, and inflammatory bowel diseases (IBD)), allergic asthma, atherosclerosis, hemophagocytic lymphohistiocytosis (HLH), Alzheimer’s disease, Parkinson’s disease and multiple sclerosis (MS) |
| UniProt | CAA31639 |
| Gene Symbol | IFNG |
| Entrez Gene ID | 3458 |
Product Documents
| Product Datasheet | Download Product Datasheet |
| COA | Contact Us |
| SDS | Download SDS |
Reviews
There are no reviews yet.