Product Type	Quantitative ELISA, Colorimetric
Product Summary	Assay Range: 15.6-1000 pg/mL Sensitivity: 10 pg/mL Sample Types: Serum, Plasma, Cell Culture Supernates Intra-Assay Precision: ≤10% Inter-Assay Precision: ≤15%
Reactivity	Human IL-2 No cross-reactivity with human cytokines
Product Components	Human IL-2 Coated Microplate, 96 well (8 x12 strips) Human IL-2 Standard, 2 vials Human IL-2 Biotinylated Antibody, 2 vials Streptavidin-HRP, 2 vials Dilution Buffer, 3 bottles Washing Buffer, 1 bottle Color Reagent (TMB), 1 bottle Stop Solution, 1 bottle Plate Sealers, 4 strips Other materials required: See Datasheet

Shipping	Shipped on blue ice
Stability & Storage	Store the unopened kit at 2-8℃, The kit is stable for 12 months. Do not use beyond expiration date.
Reconstitution	See Datasheet for Component Preparation

Alternative Names	Interleukin 2, IL2, T Cell Growth Factor, TCGF, Aldesleukin, Lymphokine
Function	Interleukin-2 (IL-2) is a cytokine primarily produced by T cells and plays a critical role in the proliferation of T cells through paracrine and autocrine activity. It further regulates immune response through promoting the differentiation of T cells into various subsets such as effector Th17 cells or regulatory T (Treg) cells. IL-2 also promotes the differentiation and stimulation of B cell and NK cell populations. The receptor for IL-2 is a heterotrimeric complex composed of IL-2 R alpha (CD25), IL-2 R beta (CD122) and IL-2 R gamma (also named, common gamma chain or CD132). IL-2 has garnered interest in cancer immunotherapy and adoptive cell therapy (ACT) where research techniques in cell culture have included IL-2 to support the expansion and survival of modified T cells in chimeric antigen receptor (CAR) T cell therapy, tumor-infiltrating lymphocyte (TIL) therapy and NK cells.
Tissue Specificity	IL-2 expression has been identified in lymph node, spleen, and brain.
Cellular Localization	Secreted protein
Involvement in Disease	IL-2 dysregulation is implicated in autoimmune disorders (rheumatoid arthritis, multiple sclerosis, and type 1 diabetes), allergic asthma, allergic rhinitis, and inflammatory bowel disease (IBD).
UniProt	P60568
Gene Symbol	IL2
Entrez Gene ID	3558

Human IL-2 Precoated ELISA Kit

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