Product Type	Quantitative ELISA, Colorimetric
Product Summary	Assay Range: 2.5-160 pg/mL Sensitivity: 1 pg/mL Sample Types: Serum, Plasma, Cell Culture Supernates Intra-Assay Precision: ≤10% Inter-Assay Precision: ≤15%
Reactivity	Human IL-4 No cross-reactivity with human cytokines
Product Components	Human IL-4 Coated Microplate, 96 well (8 x12 strips) Human IL-4 Standard, 2 vials Human IL-4 Biotinylated Antibody, 2 vials Streptavidin-HRP, 2 vials Dilution Buffer, 3 bottles Washing Buffer, 1 bottle Color Reagent (TMB), 1 bottle Stop Solution, 1 bottle Plate Sealers, 4 strips Other materials required: See Datasheet

Shipping	Shipped on blue ice
Stability & Storage	Store the unopened kit at 2-8℃, The kit is stable for 12 months. Do not use beyond expiration date.
Reconstitution	See Datasheet for Component Preparation

Alternative Names	Interleukin 4, Lymphocyte Stimulatory Factor 1, B-Cell Stimulatory Factor 1, B Cell Growth Factor 1, BCGF1, BSF1, Binetrakin, Pitrakinra, MGC79402, IL4e12, IgG1 Induction Factor
Function	Interleukin-4 (IL-4) is a cytokine involved in the regulation of immune and inflammatory responses. It promotes the differentiation of naïve T cells into Th2 cells, which in turn stimulate B cells to upregulate IgE antibodies. IL-4 is produced by mast cells, eosinophils, basophils and committed Th2 cells. There are two cell-dependent receptor complexes, either a heterodimer of IL-4 R alpha (CD124) and the common gamma chain (CD132) associated with hematopoietic cells or a heterodimer of IL-4 R alpha and IL-13 R alpha 1 (CD213A1) associated with non-hematopoietic cells.
Tissue Specificity	IL-4 expression has been identified in lymph node and placenta.
Cellular Localization	Secreted protein
Involvement in Disease	Allergic inflammation, allergic rhinitis, asthma, atopic dermatitis, autoimmune disorders (rheumatoid arthritis, systemic lupus erythematosus (SLE), and multiple sclerosis), inflammatory bowel disease (IBD) and graft-versus-host disease (GVHD).
UniProt	P05112
Gene Symbol	IL4
Entrez Gene ID	3565

Human IL-4 Precoated ELISA Kit

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