Biological Activity	Determined by in-house activity assay
Purity	Determined by SDS-PAGE and quantitative densitometry by Coomassie® Blue staining
Endotoxin	Determined by LAL method
Expression System	E. coli.
Accession Number	P35225
Sequence	Ser19-Asn132, with an N-terminal Met MSPGPVPPST ALRELIEELV NITQNQKAPL CNGSMVWSIN LTAGMYCAAL ESLINVSGCS AIEKTQRMLS GFCPHKVSAG QFSSLHVRDT KIEVAQFVKD LLLHLKKLFR EGRFN
Molecular Weight	12.7 kDa (predicted)
Formulation	Lyophilized from sterile PBS with Trehalose, pH 7.4

Shipping	Shipped at ambient temperature.
Stability & Storage	12 months from date of receipt at -20°C to -70°C, lyophilized powder. 3 months at -20°C to -70°C under sterile conditions after reconstitution. Avoid repeated freeze-thaw cycles.
Reconstitution	Reconstitute at 100 ug/mL in sterile PBS.

Alternative Names	Interleukin 13, IL13, P600, NC30, MGC116786, MGC116788, MGC116789
Function	Interleukin-13 (IL-13) is a cytokine primarily produced by T helper type 2 (Th2) cells, as well as other immune cells like mast cells, basophils, and eosinophils. It promotes the activation, differentiation, and survival of B cells, including Ig class switching. IL-13 enhances the survival and migration of epithelial cells in various organs, coupling this with its anti-parasitic Th2-mediated response in these organs. IL-13 signaling occurs when it binds IL13RA1 (CD213A1) which heterodimerizes with IL-4R alpha (CD124) to activate the JAK/STAT signal pathway.
Tissue Specificity	IL-13 expression has been identified in gastrointestinal and lung epithelial tissue.
Cellular Localization	Secreted protein
Involvement in Disease	Dysregulation of IL-13 is associated with asthma, allergic rhinitis, atopic dermatitis, scleroderma, inflammatory bowel disease (IBD), and allergic conjunctivitis.
UniProt	P35225
Gene Symbol	IL13
Entrez Gene ID	3596

Recombinant Human IL-13 Protein

Need Help Ordering?